Publications & Presentations

Publications & Presentations

The information in our publications and presentations should be considered accurate only as of the date of the publications or presentations. We disclaim any obligation to supplement or update the information in these publications and presentations.

To learn more about our innovative technology:
Drug delivery via the upper nasal space: A novel route for anesthesiologists, intensivists and emergency department physicians?

Stephen Shrewsbury, Jasna Hocevar-Trnka, and John Hoekman Full manuscript can be accessed here: https://probiologists.com/Uploads/Articles/10_637521815510349420.pdf Many drugs are effective systemically, but slow onset of non-intravenous routes of administration may limit their clinical utility. While anesthesiologists usually have intravenous (IV) access for…

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The Upper Nasal Space—A Novel Delivery Route Ideal for Central Nervous System Drugs

John Hoekman, Sutapa Ray, Sheena K Aurora, and Stephen B Shrewsbury Abstract: Solid oral dosage forms account for up to 75% of prescriptions, but their effectiveness may be limited in some patients, and inappropriate for others. While injectable formulations may…

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The SNAP 101 Double-Blind, Placebo/Active-Controlled, Safety, Pharmacokinetic, and Pharmacodynamic Study of INP105 (Nasal Olanzapine) in Healthy Adults

Stephen B. Shrewsbury, MB, ChB; Jasna Hocevar-Trnka, MD; Kelsey H. Satterly, PhD; Karen L. Craig, PhD; Jason D. Lickliter, MBBS; and John Hoekman, PhD Full manuscript can be accessed here: https://www.psychiatrist.com/JCP/article/Pages/2020/v81/19m13086.aspx Objective: INP105 is a drug-device combination of olanzapine and technology…

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